Anna Moles

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Cathepsin D is essential for the degradomic shift of macrophages required to resolve liver fibrosis
Ductular reaction-associated neutrophils promote biliary epithelium proliferation in chronic liver disease
Ductular reaction promotes intrahepatic angiogenesis through Slit2-Roundabout 1 signaling
The multifaceted role of cathepsins in liver disease
NK cells eliminate Epstein-Barr virus bound to B cells through a specific antibody-mediated uptake
Cathepsins in the Pathophysiology of Mucopolysaccharidoses: New Perspectives for Therapy
Heparan sulfate in chronic kidney diseases: Exploring the role of 3-O-sulfation
Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis
Mitochondrial-Lysosomal Axis in Acetaminophen Hepatotoxicity
The NF-κB1 is a key regulator of acute but not chronic renal injury
The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease
Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation
Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury
Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease
A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse
The c-Rel Subunit of NF-κB Regulates Epidermal Homeostasis and Promotes Skin Fibrosis in Mice
Inhibition of RelA-Ser536 Phosphorylation by a Competing Peptide Reduces Mouse Liver Fibrosis Without Blocking the Innate Immune Response
Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans
Cathepsin B Overexpression Due to Acid Sphingomyelinase Ablation Promotes Liver Fibrosis in Niemann-Pick Disease
Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease
Critical Role of Tumor Necrosis Factor Receptor 1, but not 2, in Hepatic Stellate Cell Proliferation, Extracellular Matrix Remodeling, and Liver Fibrogenesis
Acidic Sphingomyelinase Controls Hepatic Stellate Cell Activation and in Vivo Liver Fibrogenesis
Alcohol, Signaling, and ECM Turnover
Cathepsins B and D Drive Hepatic Stellate Cell Proliferation and Promote Their Fibrogenic Potential
Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-κB activation