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Cathepsin D is essential for the degradomic shift of macrophages required to resolve liver fibrosis
Paloma Ruiz-Blazquez
,
Maria Fernandez-Fernandez
,
Valeria Pistorio
,
Celia Martinez-Sanchez
,
Michele Costanzo
,
Paula Iruzubieta
,
Ekaterina Zhuravleva
,
Julia Cacho-Pujol
,
Silvia Arino
,
Alejandro Del Castillo-Cruz
,
Susana Nunez
,
Jesper B. Andersen
,
Margherita Ruoppolo
,
Javier Crespo
,
Carmen Garcia-Ruiz
,
Luigi Michele Pavone
,
Thomas Reinheckel
,
Pau Sancho-Bru
,
Mar Coll
,
Jose C. Fernandez-Checa
,
Anna Moles
Citar
DOI
Ductular reaction-associated neutrophils promote biliary epithelium proliferation in chronic liver disease
Silvia Arino
,
Beatriz Aguilar-Bravo
,
Mar Coll
,
Woo -Yong Lee
,
Moritz Peiseler
,
Paula Cantallops-Vila
,
Laura Sererols-Vinas
,
Raquel A. Martinez-Garcia de la Torre
,
Celia Martinez-Sanchez
,
Jordi Pedragosa
,
Laura Zanatto
,
Jordi Gratacos-Gines
,
Elisa Pose
,
Delia Blaya
,
Xenia Almodovar
,
Maria Fernandez-Fernandez
,
Paloma Ruiz-Blazquez
,
Juan Jose Lozano
,
Silvia Affo
,
Anna M. Planas
,
Pere Gines
,
Anna Moles
,
Paul Kubes
,
Pau Sancho-Bru
Citar
DOI
Ductular reaction promotes intrahepatic angiogenesis through Slit2-Roundabout 1 signaling
Mar Coll
,
Silvia Arino
,
Celia Martinez-Sanchez
,
Ester Garcia-Pras
,
Javier Gallego
,
Anna Moles
,
Beatriz Aguilar-Bravo
,
Delia Blaya
,
Julia Vallverdu
,
Teresa Rubio-Tomas
,
Juan Jose Lozano
,
Elisa Pose
,
Isabel Graupera
,
Andrea Fernandez-Vidal
,
Albert Pol
,
Ramon Bataller
,
Jian-Guo Geng
,
Pere Gines
,
Mercedes Fernandez
,
Pau Sancho-Bru
Citar
DOI
The multifaceted role of cathepsins in liver disease
Paloma Ruiz-Blazquez
,
Valeria Pistorio
,
Maria Fernandez-Fernandez
,
Anna Moles
Citar
DOI
NK cells eliminate Epstein-Barr virus bound to B cells through a specific antibody-mediated uptake
Elisenda Alari-Pahissa
,
Michelle Ataya
,
Ilias Moraitis
,
Miriam Campos-Ruiz
,
Mireia Altadill
,
Aura Muntasell
,
Anna Moles
,
Miguel Lopez-Botet
Citar
DOI
Cathepsins in the Pathophysiology of Mucopolysaccharidoses: New Perspectives for Therapy
Valeria De Pasquale
,
Anna Moles
,
Luigi Michele Pavone
Citar
DOI
Heparan sulfate in chronic kidney diseases: Exploring the role of 3-O-sulfation
Laura Ferreras
,
Anna Moles
,
Gerhard R. Situmorang
,
Rana el Masri
,
Imogen L. Wilson
,
Katie Cooke
,
Emily Thompson
,
Marion Kusche-Gullberg
,
Romain R. Vives
,
Neil S. Sheerin
,
Simi Ali
Citar
DOI
Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis
Jonathan Martinez-Fabregas
,
Alan Prescott
,
Sander van Kasteren
,
Deena Leslie Pedrioli
,
Irwin McLean
,
Anna Moles
,
Thomas Reinheckel
,
Valeria Poli
,
Colin Watts
Citar
DOI
Mitochondrial-Lysosomal Axis in Acetaminophen Hepatotoxicity
Anna Moles
,
Sandra Torres
,
Anna Baulies
,
Carmen Garcia-Ruiz
,
Jose C. Fernandez-Checa
Citar
DOI
The NF-κB1 is a key regulator of acute but not chronic renal injury
Amy Fearn
,
Gerhard R. Situmorang
,
Christopher Fox
,
Fiona Oakley
,
Rachel Howarth
,
Caroline L. Wilson
,
Agklinta Kiosia
,
Michael G. Robson
,
Derek A. Mann
,
Anna Moles
,
Neil S. Sheerin
Citar
DOI
The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease
Pasquale Cocchiaro
,
Valeria De Pasquale
,
Rossella Della Morte
,
Simona Tafuri
,
Luigi Avallone
,
Anne Pizard
,
Anna Moles
,
Luigi Michele Pavone
Citar
DOI
Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation
Alvaro de Mingo
,
Estefania de Gregorio
,
Anna Moles
,
Nuria Tarrats
,
Anna Tutusaus
,
Anna Colell
,
Jose C. Fernandez-Checa
,
Albert Morales
,
Montserrat Mari
Citar
DOI
A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer
A. Moles
,
J. A. Butterworth
,
A. Sanchez
,
J. E. Hunter
,
J. Leslie
,
H. Sellier
,
D. Tiniakos
,
S. J. Cockell
,
D. A. Mann
,
F. Oakley
,
N. D. Perkins
Citar
DOI
Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury
Pasquale Cocchiaro
,
Christopher Fox
,
Nicholas W. Tregidgo
,
Rachel Howarth
,
Katrina M. Wood
,
Gerhard R. Situmorang
,
Luigi M. Pavone
,
Neil S. Sheerin
,
Anna Moles
Citar
DOI
Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease
Christopher Fox
,
Pasquale Cocchiaro
,
Fiona Oakley
,
Rachel Howarth
,
Krystena Callaghan
,
Jack Leslie
,
Saimir Luli
,
Katrina M. Wood
,
Federica Genovese
,
Neil S. Sheerin
,
Anna Moles
Citar
DOI
A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse
Anna Moles
,
Lindsay Murphy
,
Caroline L. Wilson
,
Jayashree Bagchi Chakraborty
,
Christopher Fox
,
Eek Joong Park
,
Jelena Mann
,
Fiona Oakley
,
Rachel Howarth
,
John Brain
,
Steven Masson
,
Michael Karin
,
Ekihiro Seki
,
Derek A. Mann
Citar
DOI
The c-Rel Subunit of NF-κB Regulates Epidermal Homeostasis and Promotes Skin Fibrosis in Mice
Nicola Fullard
,
Anna Moles
,
Steven O'Reilly
,
Jacob M. van Laar
,
David Faini
,
Julie Diboll
,
Nick J. Reynolds
,
Derek A. Mann
,
Julia Reichelt
,
Fiona Oakley
Citar
DOI
Inhibition of RelA-Ser536 Phosphorylation by a Competing Peptide Reduces Mouse Liver Fibrosis Without Blocking the Innate Immune Response
Anna Moles
,
Ana M. Sanchez
,
Paul S. Banks
,
Lindsay B. Murphy
,
Saimir Luli
,
Lee Borthwick
,
Andrew Fisher
,
Steven O'Reilly
,
Jacob M. van Laar
,
Steven A. White
,
Neil D. Perkins
,
Alastair D. Burt
,
Derek A. Mann
,
Fiona Oakley
Citar
DOI
Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans
James Pritchett
,
Emma Harvey
,
Varinder Athwal
,
Andrew Berry
,
Cliff Rowe
,
Fiona Oakley
,
Anna Moles
,
Derek A. Mann
,
Nicoletta Bobola
,
Andrew D. Sharrocks
,
Brian J. Thomson
,
Abed M. Zaitoun
,
William L. Irving
,
Indra N. Guha
,
Neil A. Hanley
,
Karen Piper Hanley
Citar
DOI
Cathepsin B Overexpression Due to Acid Sphingomyelinase Ablation Promotes Liver Fibrosis in Niemann-Pick Disease
Anna Moles
,
Nuria Tarrats
,
Jose C. Fernandez-Checa
,
Montserrat Mari
Citar
DOI
Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease
Mohammad R. Ebrahimkhani
,
Fiona Oakley
,
Lindsay B. Murphy
,
Jelena Mann
,
Anna Moles
,
Maria J. Perugorria
,
Elizabeth Ellis
,
Anne F. Lakey
,
Alastair D. Burt
,
Angela Douglass
,
Matthew C. Wright
,
Steven A. White
,
Fabrice Jaffre
,
Luc Maroteaux
,
Derek A. Mann
Citar
DOI
Critical Role of Tumor Necrosis Factor Receptor 1, but not 2, in Hepatic Stellate Cell Proliferation, Extracellular Matrix Remodeling, and Liver Fibrogenesis
Nuria Tarrats
,
Anna Moles
,
Albert Morales
,
Carmen Garcia-Ruiz
,
Jose C. Fernandez-Checa
,
Montserrat Mari
Citar
DOI
Acidic Sphingomyelinase Controls Hepatic Stellate Cell Activation and in Vivo Liver Fibrogenesis
Anna Moles
,
Nuria Tarrats
,
Albert Morales
,
Marlene Dominguez
,
Ramon Bataller
,
Juan Caballeria
,
Carmen Garcia-Ruiz
,
Jose C. Fernandez-Checa
,
Montserrat Mari
Citar
DOI
Alcohol, Signaling, and ECM Turnover
Devanshi Seth
,
Nympha B. D'Souza El-Guindy
,
Minoti Apte
,
Montserrat Mari
,
Steven Dooley
,
Manuela Neuman
,
Paul S. Haber
,
Gopal C. Kundu
,
Agus Darwanto
,
Willem J. de Villiers
,
A. Vonlaufen
,
Z. Xu
,
P. Phillips
,
S. Yang
,
D. Goldstein
,
R. M. Pirola
,
J. S. Wilson
,
Anna Moles
,
Anna Fernandez
,
Anna Colell
,
Carmen Garcia-Ruiz
,
Jose C. Fernandez-Checa
,
Christoph Meyer
,
Nadja M. Meindl-Beinker
Citar
DOI
Cathepsins B and D Drive Hepatic Stellate Cell Proliferation and Promote Their Fibrogenic Potential
Anna Moles
,
Nuria Tarrats
,
Jose C. Fernandez-Checa
,
Montserrat Mari
Citar
DOI
Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-κB activation
Montserrat Mari
,
Anna Colell
,
Albert Morales
,
Francisco Caballero
,
Anna Moles
,
Anna Fernandez
,
Oihana Terrones
,
Gorka Basanez
,
Bruno Antonsson
,
Carmen Garcia-Ruiz
,
Jose C. Fernandez-Checa
Citar
DOI
An in situ perfusion protocol of rat epididymal adipose tissue useful in metabolic studies
G Cònsol
,
A Moles
,
D Ricart-Jané
,
M Llobera
Citar
DOI
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